Short Title:Protein Biochemistry
Full Title:Protein Biochemistry
Module Code:PROT H4001
Credits: 5
Field of Study:Biology and biochemistry
Module Delivered in 1 programme(s)
Reviewed By:JOHN BEHAN
Module Author:JOHN BEHAN
Module Description:Proteins are sometimes referred to as ‘the workhorses of biology’. As our understanding and knowledge about the human and other genomes increases, attention is shifting towards a new paradigm in biology with proteins increasingly taking a centre stage. A detailed and critical understanding of protein structure, function and applications is increasingly important for working biochemists. The advent of proteomic science is likely to see a surge of interest in proteins and their roles in biochemical processes. It is intended that this module will provide a detailed insight into selected aspects of modern protein biochemistry relevant to current and future trends in bioanalysis. The course aims to support other modules of the degree by giving students an understanding of the underlying principles of specific topics of growing importance in modern bioanalysis.
Learning Outcomes
On successful completion of this module the learner will be able to:
LO1 Have a critical knowledge of the elements of protein structure and folding
LO2 Possess critical awareness of peptide biodiversity and its’ potential applications in immunology and rational drug design
LO3 Be able to describe in detail the optimisation of final stage processes for protein therapeutics
LO4 Be able to critically discuss lyophillization processes to maximise product stability
LO5 Be able describe and discuss factors in the formulation a final protein or peptide product.

Module Content & Assessment

Course Work
Assessment Type Assessment Description Outcome addressed % of total Assessment Date
Continuous Assessment Continuous assessments   30.00 n/a
End of Module Formal Examination
Assessment Type Assessment Description Outcome addressed % of total Assessment Date
Formal Exam End-of-Semester Final Examination   70.00 End-of-Semester

TU Dublin – Tallaght Campus reserves the right to alter the nature and timings of assessment


Module Workload

This module has no Full Time workload.
This module has no Part Time workload.

Module Resources

Required Book Resources
  • Mathews, C.K., van Holde, K.E. and Ahern, K.G 1999, Biochemistry, Addison Wesley Longman
Recommended Book Resources
  • Voet, D. and Voet, J.G 2204, Biochemistry,, Wiley & Sons
  • Berg, J.M., Tymoczko, J.L. and Stryer, L 2006, Biochemistry, W.H. Freeman
  • Wu-pong, S., Rojanasakul, Y. and Robinson, J 2008, Biopharmaceutical Drug Design and Development, Humana Press
  • Reid, R.E. and Dekker, M 1999, Peptide and Protein Drug Analysis, CRC Press
  • Wang, Y.J. and Pearlsman, R 1993, Stability and Characterisation of Protein and Peptide Drugs: Case Histories, Springer
Required Article/Paper Resources
  • Selected articles from Pharmaceutical Technology Europe, Immunology Today
  • Selected Journal and Review articles from scientific journals
Other Resources
  • Case Studies: Case studies.

Module Delivered in

Programme Code Programme Semester Delivery
TA_SBIOL_B (1 year add on) Bachelor of Science (Honours) in Bioanalytical Science 7 Mandatory