Short Title:API Process and Spectroscopy
Full Title:API Process and Spectroscopy
Language of Instruction:English
Module Code:MANU H2041
Credits: 5
Field of Study:Science
Module Delivered in 3 programme(s)
Reviewed By:JOHN BEHAN
Module Description:This module aims to provide the student with a knowledge of the manufacturing and testing of active pharmaceutical ingredients (API). The second part of this module will provide the knowledge and skills necessary for the analysis of samples using spectroscopic techniques.
Learning Outcomes
On successful completion of this module the learner will be able to:
LO1 Illustrate operations involved in the synthesis and purification of active pharmaceutical ingredients
LO2 Describe the equipment used in a bulk pharmaceutical plant and its operation.
LO3 Explain the considerations when scaling up a manufacturing process
LO4 Describe the industrial wastewater treatment options
LO5 Understand the principles of operation of standard spectroscopic instrumentation and select the most appropriate method of sample preparation for each spectroscopic technique
LO6 Set up and operate spectroscopic instruments
LO7 Troubleshoot and describe accuracy and precision limitations applicable to each technique
LO8 Analyse samples quantitatively by UV, AAS and IR spectrophotometry

Module Content & Assessment

Course Work
Assessment Type Assessment Description Outcome addressed % of total Assessment Date
Continuous Assessment A series of in class tests together with on-line/off-line activities will form the basis of this component. 1,2,3,4,5,6,7,8 30.00 n/a
End of Module Formal Examination
Assessment Type Assessment Description Outcome addressed % of total Assessment Date
Formal Exam End-of-Semester Final Examination 1,2,3,4,5,6,7,8 70.00 End-of-Semester

TU Dublin – Tallaght Campus reserves the right to alter the nature and timings of assessment


Module Workload

Workload: Full Time
Workload Type Workload Description Hours Frequency Average Weekly Learner Workload
Lecture Weekly lecture material 4.00 Every Week 4.00
Independent Learning Engagement with on-line activities, review of course material with additional recommended resources as required. 4.00 Every Week 4.00
Total Weekly Learner Workload 8.00
Total Weekly Contact Hours 4.00
This module has no Part Time workload.

Module Resources

Required Book Resources
  • JA Moulijn; M Makkee; A Van Diepen 2001, Chemical Process Technology, J. Wiley and Sons
  • David J. am Ende 2010, Chemical Engineering in the Pharmaceutical Industry, Wiley [ISBN: 978-0-470-42669-2]
  • Gary D. Christian,Purnendu K. Dasgupta,Kevin A. Schug 2013, Analytical Chemistry, 7th Ed Ed., Wiley [ISBN: 9780470887578]
  • Daniel C. Harris 2010, Quantitative Chemical Analysis, 8th Ed. Ed., Macmillan [ISBN: 9781429218153]
Recommended Book Resources
  • Francis X. McConville 2006, The Pilot Plant Real Book, 2nd Ed Ed., Fxm Engineering & Design [ISBN: 9780972176927]
  • Richard M. Felder,Ronald W. Rousseau,Lisa G. Bullard 2015, Elementary Principles of Chemical Processes, 4th Ed Ed., John Wiley & Sons [ISBN: 9781118431221]
  • A. John Blacker,Mike T. Williams 2011, Pharmaceutical Process Development: Current Chemical and Engineering Challenges, Royal Society of Chemistry [ISBN: 978-1849731461]
  • Mary K. Moore,Elmer B. Ledesma 2015, Academia and Industrial Pilot Plant Operations and Safety, Amer Chemical Society [ISBN: 9780841229600]
This module does not have any article/paper resources
Other Resources

Module Delivered in

Programme Code Programme Semester Delivery
TA_SPHAR_B Bachelor of Science (Honours) in Pharmaceutical Science 4 Mandatory
TA_SASCI_D Bachelor of Science in Bioanalysis or Chemical Analysis 4 Group Elective 2
TA_SAPHR_D Bachelor of Science in Pharmaceutical Science 4 Mandatory