Short Title:Manufacturing Technology
Full Title:Manufacturing Technology
Language of Instruction:English
Module Code:MANU H4040
 
Credits: 5
Field of Study:Pharmacy
Module Delivered in 1 programme(s)
Reviewed By:JOHN BEHAN
Module Author:ADRIENNE FLEMING
Module Description:Ths purpose of this module is to provide the student with an in-depth knowledge of drug processing from lead compound selection to finished product, focusing on key critical attributes such as scale-up, process optimisation, technology transfer, crystallisation, and control systems
Learning Outcomes
On successful completion of this module the learner will be able to:
LO1 Develop a drug process large scale production from research phase
LO2 Use a knowledge of integrated technologies to identify and address the challenges associated with the manufacture of drug products
LO3 Identify and address the challenges associated with crystallisation and polymorphism in drug active compounds
LO4 Characterise and analyse crystals
LO5 Identify critical process parameters and analytical techniques for monitoring drug production stages
 

Module Content & Assessment

Course Work
Assessment Type Assessment Description Outcome addressed % of total Assessment Date
Continuous Assessment Online exams within the semester In class CA 1,2,3,4,5 30.00 Ongoing
End of Module Formal Examination
Assessment Type Assessment Description Outcome addressed % of total Assessment Date
Formal Exam End-of-Semester Final Examination 1,2,3,4,5 70.00 End-of-Semester

TU Dublin – Tallaght Campus reserves the right to alter the nature and timings of assessment

 

Module Workload

Workload: Full Time
Workload Type Workload Description Hours Frequency Average Weekly Learner Workload
Lecture Theory, Lab Simulations and Case Studies 4.00 Every Week 4.00
Independent Learning Independent study, preparation of asignment, report on laboratory simulation for process control, preparation for written CA, final exam preparation 4.00 Every Week 4.00
Total Weekly Learner Workload 8.00
Total Weekly Contact Hours 4.00
This module has no Part Time workload.
 

Module Resources

Required Book Resources
  • Ian Houson (Editor) 2011, Process Understanding, Wiley [ISBN: 978-3-527-32584-9]
  • Martin Rhodes 2008, Introduction to particle technology, Wiley [ISBN: 978-0-470-01427-1]
  • Michael E. Aulton 2007, Aulton's Pharmaceutics, The Design and Manufacture of Medicines, 3rd Edition Ed., Churchill Livingstone [ISBN: 9780443101083]
Recommended Book Resources
  • JA Moulijn; M Makkee; A Van Diepen. J. 2001, Chemical Process Technology, Wiley & Sons
  • Derek Walker,D Walker 2008, The Management of Chemical Process Development in the Pharmaceutical Industry, Wiley [ISBN: 978-0-470-17156-1]
  • C. Someswara Rao 2007, The chemistry of process development in fine chemical & pharmaceutical industry, 2nd ed. Ed., J. Wiley Chichester [ISBN: 978-0-470-31995-6]
  • Hsien-Hsin Tung... [et al.] 2009, Crystallization of Organic Compounds, Wiley Hoboken, N.J. [ISBN: 978-0-471-46780-9]
  • Katherine Bakeev (Editor) 2010, Process Analytical Technology: Spectroscopic Tools and Implementation Strategies for the Chemical and Pharmaceutical Industries, 2nd Ed. Ed. [ISBN: 978-0-470-72207-7]
  • Myke King, 2010, Process Control: A Practical Approach [ISBN: 978-0-470-97587-9]
  • W. Zhang, B. Cue 2012, Green Techniques for Organic Synthesis and Medicinal Chemistry, Wiley [ISBN: 978-0-470-71151-4]
  • John H. Atherton, Keith J. Carpenter 2000, Process development: Physicochemical Concepts, Oxford University Press [ISBN: 978-0-19-850372-9]
  • Trevor Kletz 2006, Hazop and Hazan, 4th edition Ed., Institution of Chemical Engineers Rugby [ISBN: 978052955062]
  • Christopher Hammond 2001, The basics of crystallography and diffraction, Oxford University Press Oxford [ISBN: 0198505523]
  • Richard Turton... [et al.] 2009, Analysis, synthesis, and design of chemical processes, Prentice Hall Upper Saddle River, N.J. [ISBN: 0135129664]
  • Bruce Finlayson 2012, Chemical Engineering Computing, 2 Ed., Wiley [ISBN: 0470932953]
  • by Warren D. Seider... [et al.] 2009, Product and process design principles, John Wiley Hoboken, NJ [ISBN: 0470048956]
  • Nayef Ghasem 2011, Computer Methods in Chemical Engineering, CRC [ISBN: 1439849994]
This module does not have any article/paper resources
This module does not have any other resources
 

Module Delivered in

Programme Code Programme Semester Delivery
TA_SPHAR_B Bachelor of Science (Honours) in Pharmaceutical Science 8 Mandatory